Regina operated her janitorial business diligently for many years before retiring. She attended school 42 and graduated from NorthWest HighSchool. She enjoyed the outdoors and fishing. <br />
She was preceded in death by her father, Gene Howard; mother, Dolly Ann Howard Davenport; and six siblings, Humphrey Howard, Sharon Jean Howard, Lowel Howard, Gene Howard Jr. & Karollatta Gail Howard. She leaves cherishing her memory, her sons, Robert Hartley & Reggie Hartley; granddaughter Daniela Hartley; siblings, Donnie Joe Howard, Arlane Orris Howard, Pamela Kay Waller & Hanson Mark Howard; her loving husband of 20 years, Clarence E. Mayes; and a host of other family and friends. <br />
Her remains will be placed alongside her husband in Millsborough, DE.